Sophie Layton trained at Camberwell School of Art and completed a degree in Fine Art Printmaking at the University of Brighton in 2009. Two works from her degree show were selected for inclusion in the Aldrich collection and several others were acquired for private collections. Layton's work has featured in a number of exhibitions internationally. She has had three solo exhibitions at Eames Fine Art; outside of the UK, she has been included in exhibitions in Japan, Sweden, China, Poland, and Italy; and she has exhibited work several times at the London Original Print Fair and the Royal Academy Summer Exhibition. She was nominated for the Queen Sonja Print Award in 2019.

Layton's work includes series of monotypes that explore light and aim to create expression through the use of subtle colour and a rich, painterly quality in print. She uses tones placed side by side to evoke qualities of light and shifts of mood. In 2017, Layton was accepted to a residency at three different printmaking studios in Japan at which she learned the mokuhanga printing technique. This has been incorporated into her practice to enhance the translucence of her colours. She now has also expanded her monotypes to include Ikebana flower arrangements as their subjects.

Sophie Layton lives and works in London.